{ "_id": "6ae5b1b73d0f299392dd460c", "Package": "ZetaSuite", "Type": "Package", "Title": "Analyze High-Dimensional High-Throughput Dataset and Quality\nControl Single-Cell RNA-Seq", "Version": "1.0.2", "Date": "2025-09-24", "Authors@R": "c(\nperson(given = \"Yajing\", family = \"Hao\", email = \"yahao@health.ucsd.edu\", role = c(\"aut\"), comment = c(ORCID = \"0000-0003-1384-4176\")),\nperson(given = \"Shuyang\", family = \"Zhang\", email = \"s4zhang@ucsd.edu\", role = \"ctb\", comment=c(ORCID=\"0000-0002-8428-1828\")),\nperson(given = \"Junhui\", family = \"Li\", email = \"ljh.biostat@gmail.com\", role = \"cre\", comment=c(ORCID=\"0000-0003-3973-1700\")),\nperson(given = \"Guofeng\", family = \"Zhao\", email = \"gzhao@health.ucsd.edu\", role = \"ctb\"),\nperson(given = \"Xiang-Dong\", family = \"Fu\", email = \"xdfu@health.ucsd.edu\", role = c(\"cph\",\"fnd\"), comment = c(ORCID = \"0000-0001-5499-8732\"))\n)", "Maintainer": "Junhui Li ", "Description": "The advent of genomic technologies has enabled the\ngeneration of two-dimensional or even multi-dimensional\nhigh-throughput data, e.g., monitoring multiple changes in gene\nexpression in genome-wide siRNA screens across many different\ncell types (E Robert McDonald 3rd (2017) and Tsherniak A (2017) ) or single cell transcriptomics\nunder different experimental conditions. We found that simple\ncomputational methods based on a single statistical criterion\nis no longer adequate for analyzing such multi-dimensional\ndata. We herein introduce 'ZetaSuite', a statistical package\ninitially designed to score hits from two-dimensional RNAi\nscreens.We also illustrate a unique utility of 'ZetaSuite' in\nanalyzing single cell transcriptomics to differentiate rare\ncells from damaged ones (Vento-Tormo R (2018) ). In 'ZetaSuite', we have the\nfollowing steps: QC of input datasets, normalization using\nZ-transformation, Zeta score calculation and hits selection\nbased on defined Screen Strength.", "BugReports": "https://github.com/JunhuiLi1017/ZetaSuite/issues", "License": "MIT + file LICENSE", "RoxygenNote": "7.3.2", "VignetteBuilder": "knitr", "Author": "Yajing Hao [aut] (),\nShuyang Zhang [ctb] (),\nJunhui Li [cre] (),\nGuofeng Zhao [ctb], Xiang-Dong Fu [cph, fnd]\n()", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-31 08:38:53 UTC", "User": "root" }, "Encoding": "UTF-8", "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev\nzlib1g-dev", "Repository": "https://junhuili1017.r-universe.dev", "Date/Publication": "2025-09-24 20:33:44 UTC", "RemoteUrl": "https://github.com/junhuili1017/zetasuite", "RemoteRef": "HEAD", "RemoteSha": "2903973acbadf45aa9894329a3d9f83885ec6030", "_user": "junhuili1017", "_type": "src", "_file": "ZetaSuite_1.0.2.tar.gz", "_fileid": 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